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Valategrast
CAS No. 220847-86-9
Valategrast( —— )
Catalog No. M13520 CAS No. 220847-86-9
Valategrast is a potent, α4β1 (VLA-4) and α4β7 dual antagonist.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 5MG | 284 | Get Quote |
|
| 50MG | 1341 | Get Quote |
|
| 100MG | 2196 | Get Quote |
|
| 200MG | Get Quote | Get Quote |
|
| 500MG | Get Quote | Get Quote |
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| 1G | Get Quote | Get Quote |
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Biological Information
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Product NameValategrast
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NoteResearch use only, not for human use.
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Brief DescriptionValategrast is a potent, α4β1 (VLA-4) and α4β7 dual antagonist.
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DescriptionValategrast is a potent, α4β1 (VLA-4) and α4β7 dual antagonist.Asthma Discontinued.
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In VitroValategrast contains a common l-phenylalanine-N-aroyl motif where the carboxylic acid is responsible for binding to the metal ion in the metal-ion-dependent adhesion site (MIDAS).
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In Vivo——
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Synonyms——
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PathwayCell Cycle/DNA Damage
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TargetIntegrin
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RecptorIntegrin
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Research AreaInflammation/Immunology
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IndicationAsthma
Chemical Information
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CAS Number220847-86-9
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Formula Weight604.953
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Molecular FormulaC30H32Cl3N3O4
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Purity>98% (HPLC)
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SolubilityIn Vitro:?DMSO : 170 mg/mL (281.01 mM)
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SMILESCCN(CC)CCOC(=O)C(CC1=CC=C(C=C1)NC(=O)C2=C(C=CC=C2Cl)Cl)NC(=O)C3=C(C=CC=C3Cl)C
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Chemical Name2-(diethylamino)ethyl (2S)-2-[(2-chloro-6-methylbenzoyl)amino]-3-[4-[(2,6-dichlorobenzoyl)amino]phenyl]propanoate
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Sidduri A, et al. Bioorg Med Chem Lett. 2002 Sep 2;12(17):2479-82.
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Valategrast
Valategrast is a potent, α4β1 (VLA-4) and α4β7 dual antagonist.
