Cart
sales@molnova.com
VHL-IN-15
CAS No. 1360616-29-0
VHL-IN-15( VHL-IN 15 | VHL IN-15 | VHL-IN-15 )
Catalog No. M11483 CAS No. 1360616-29-0
VHL-IN-15 is a potent (IC50=4.1 uM) von Hippel–Lindau protein (VHL) ligand that disrupts the VHL/HIF-1α interaction.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 100MG | Get Quote | Get Quote |
|
| 200MG | Get Quote | Get Quote |
|
| 500MG | Get Quote | Get Quote |
|
| 1G | Get Quote | Get Quote |
|
Biological Information
-
Product NameVHL-IN-15
-
NoteResearch use only, not for human use.
-
Brief DescriptionVHL-IN-15 is a potent (IC50=4.1 uM) von Hippel–Lindau protein (VHL) ligand that disrupts the VHL/HIF-1α interaction.
-
DescriptionVHL-IN-15 is a potent (IC50=4.1 uM) von Hippel–Lindau protein (VHL) ligand that disrupts the VHL/HIF-1α interaction.
-
In Vitro——
-
In Vivo——
-
SynonymsVHL-IN 15 | VHL IN-15 | VHL-IN-15
-
PathwayProteasome/Ubiquitin
-
TargetE3 Ubiquitin Ligase
-
RecptorE3 Ubiquitin Ligase
-
Research Area——
-
Indication——
Chemical Information
-
CAS Number1360616-29-0
-
Formula Weight410.43
-
Molecular FormulaC21H22N4O5
-
Purity>98% (HPLC)
-
Solubility——
-
SMILESO=C([C@H]1N(C(CC2=CC(C)=NO2)=O)C[C@H](O)C1)NCC3=CC=C(C4=CN=CO4)C=C3
-
Chemical Name(2S,4R)-4-hydroxy-1-(2-(3-methylisoxazol-5-yl)acetyl)-N-(4-(oxazol-5-yl)benzyl)pyrrolidine-2-carboxamide
Shipping & Storage Information
-
Storage(-20℃)
-
ShippingWith Ice Pack
-
Stability≥ 2 years
Reference
1. Buckley DL, et al. J Am Chem Soc. 2012 Mar 14;134(10):4465-8.
2. Van Molle I, et al. Chem Biol. 2012 Oct 26;19(10):1300-12.
molnova catalog
related products
-
BRD5529
BRD5529 is a small-molecule inhibitor that disrupts the interaction of CARD9-E3 ubiquitin ligase TRIM62 with IC50 of 8.6 uM.
-
inh-02
inh-02 (RNF5 inhibitor inh-02) is a novel small molecule inhibitor of E3 ubiquitin ligase RNF5/RMA1.
-
Heclin
A small molecule inhibitor of HECT-type ubiquitin ligase with IC50 of 6.8/6.3/6.9 uM for Smurf2/Nedd4/WWP1, respectively.
