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VH032-cyclopropane-F

CAS No. 2306193-99-5

VH032-cyclopropane-F( VHL ligand 3 | E3 ligase Ligand 19 | Phenolic VH101 )

Catalog No. M26942 CAS No. 2306193-99-5

VH032-cyclopropane-F is a VH032-based VHL ligand. VH032-cyclopropane-F can be connected to the ligand for protein by a linker to form PROTACs. PROTAC 1 is a partial degrader of SMARCA2 and SMARCA4.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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10MG 86 In Stock
25MG 143 In Stock
50MG 214 In Stock
100MG 325 In Stock
200MG 525 In Stock
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Biological Information

  • Product Name
    VH032-cyclopropane-F
  • Note
    Research use only, not for human use.
  • Brief Description
    VH032-cyclopropane-F is a VH032-based VHL ligand. VH032-cyclopropane-F can be connected to the ligand for protein by a linker to form PROTACs. PROTAC 1 is a partial degrader of SMARCA2 and SMARCA4.
  • Description
    VH032-cyclopropane-F is a VH032-based VHL ligand. VH032-cyclopropane-F can be connected to the ligand for protein by a linker to form PROTACs. PROTAC 1 is a partial degrader of SMARCA2 and SMARCA4.
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    VHL ligand 3 | E3 ligase Ligand 19 | Phenolic VH101
  • Pathway
    Others
  • Target
    Other Targets
  • Recptor
    RGS19| RGS4
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    2306193-99-5
  • Formula Weight
    532.63
  • Molecular Formula
    C26H33FN4O5S
  • Purity
    >98% (HPLC)
  • Solubility
    In Vitro:?DMSO : 100 mg/mL (187.75 mM)
  • SMILES
    Cc1ncsc1-c1ccc(CNC(=O)[C@@H]2C[C@@H](O)CN2C(=O)[C@@H](NC(=O)C2(F)CC2)C(C)(C)C)c(O)c1
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Blazer LL, et al. Reversible, allosteric small-molecule inhibitors of regulator of G protein signaling proteins. Mol Pharmacol. 2010 Sep;78(3):524-33.
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