Cart
sales@molnova.com
Uprifosbuvir
CAS No. 1496551-77-9
Uprifosbuvir( MK3682 | IDX 21437 )
Catalog No. M12075 CAS No. 1496551-77-9
A novel uridine nucleotide analog HCV NS5B polymerase inhibitor for treatment of HCV infection combined with Grazoprevir and Ruzasvir.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 5MG | 1323 | Get Quote |
|
| 50MG | 2682 | Get Quote |
|
| 100MG | 3600 | Get Quote |
|
| 200MG | Get Quote | Get Quote |
|
| 500MG | Get Quote | Get Quote |
|
| 1G | Get Quote | Get Quote |
|
Biological Information
-
Product NameUprifosbuvir
-
NoteResearch use only, not for human use.
-
Brief DescriptionA novel uridine nucleotide analog HCV NS5B polymerase inhibitor for treatment of HCV infection combined with Grazoprevir and Ruzasvir.
-
DescriptionA novel uridine nucleotide analog HCV NS5B polymerase inhibitor for treatment of HCV infection combined with Grazoprevir and Ruzasvir.HCV Infection Phase 2 Clinical.
-
In Vitro——
-
In Vivo——
-
SynonymsMK3682 | IDX 21437
-
PathwayMicrobiology/Virology
-
TargetHCV
-
RecptorHCV
-
Research AreaInfection
-
Indication——
Chemical Information
-
CAS Number1496551-77-9
-
Formula Weight545.91
-
Molecular FormulaC22H29ClN3O9P
-
Purity>98% (HPLC)
-
SolubilityIn Vitro:?DMSO : 250 mg/mL (457.95 mM)
-
SMILESC[C@@H](C(OC(C)C)=O)N[P@@](OC1=CC=CC=C1)(OC[C@H]2O[C@@H](N(C(N3)=O)C=CC3=O)[C@](C)(Cl)[C@@H]2O)=O
-
Chemical NamePropan-2-yl (2R)-2-{[(R)-({(2R,3R,4R,5R)-4-chloro-5-[2,4-dioxo-3,4dihydropyrimidin-1(2H)-yl]-3-hydroxy-4-methyloxolan-2yl}methoxy)(phenoxy)phosphoryl]amino}propanoate
Shipping & Storage Information
-
Storage(-20℃)
-
ShippingWith Ice Pack
-
Stability≥ 2 years
Reference
1. Wyles D, et al. Hepatology. 2017 Jul 7. doi: 10.1002/hep.29358.
2. Lawitz E, et al. Lancet Gastroenterol Hepatol. 2017 Aug 9. pii: S2468-1253(17)30163-2.
molnova catalog
related products
-
Beclabuvir hydrochlo...
Beclabuvir (BMS-791325) is a potent allosteric inhibitor of HCV NS5B polymerase with EC50 of 6 and 3 nM for genotype 1b and 1a in FRET assays, respectively.
-
Paritaprevir
Paritaprevir (ABT-450, Veruprevir) is a potent HCV NS3/4A protease inhibitor with EC50 of 1 and 0.21 nM for HCV GT 1a and 1b, respectively.
-
Narirutin
Narirutin has anti-allergic and anti-inflammatory properties, can reduce airway inflammation in ovalbumin (OVA)-sensitized / challenged NC / Nga mice, a model of allergic eosinophilic airway inflammation.
