USL311
CAS No. 1373268-67-7
USL311( —— )
Catalog No. M22471 CAS No. 1373268-67-7
USL311 is a CXCR4 receptor antagonist which prevents the binding of stromal-cell derived factor-1 (SDF-1 or CXCL12) to CXCR4. USL311 inhibits CXCR4 activation and decreases proliferation and migration of CXCR4-expressing tumor cells, with anti-tumor activity.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 2MG | 106 | In Stock |
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| 5MG | 178 | In Stock |
|
| 10MG | 259 | In Stock |
|
| 25MG | 434 | In Stock |
|
| 50MG | 627 | In Stock |
|
| 100MG | 893 | In Stock |
|
| 500MG | 1782 | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
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Product NameUSL311
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NoteResearch use only, not for human use.
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Brief DescriptionUSL311 is a CXCR4 receptor antagonist which prevents the binding of stromal-cell derived factor-1 (SDF-1 or CXCL12) to CXCR4. USL311 inhibits CXCR4 activation and decreases proliferation and migration of CXCR4-expressing tumor cells, with anti-tumor activity.
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DescriptionUSL311 is a CXCR4 receptor antagonist which prevents the binding of stromal-cell derived factor-1 (SDF-1 or CXCL12) to CXCR4. USL311 inhibits CXCR4 activation and decreases proliferation and migration of CXCR4-expressing tumor cells, with anti-tumor activity.
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In Vitro——
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In Vivo——
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Synonyms——
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PathwayAutophagy
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TargetCXCR
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RecptorCXCR4
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Research AreaCancer
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IndicationSolid Tumors (Phase 1)Relapsed/Recurrent GBM (Phase 2)
Chemical Information
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CAS Number1373268-67-7
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Formula Weight422.57
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Molecular FormulaC24H34N6O
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Purity>98% (HPLC)
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SolubilityDMSO:24 mg/mL (59.79 mM; Need ultrasonic)
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SMILESCC(C)N1CCC(CC1)N1CCCN(CC1)c1cccc(n1)C(=O)Nc1ccncc1
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Peter Richardson. Usl-311 for use in the treatment of cancer. WO2018162924A1
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