Cart
sales@molnova.com
UNC926 hydrochloride
CAS No. 1782573-49-2
UNC926 hydrochloride( —— )
Catalog No. M23797 CAS No. 1782573-49-2
UNC926 hydrochloride is a methyl-lysine (Kme) reader domain inhibitor.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 5MG | 272 | In Stock |
|
| 10MG | 408 | In Stock |
|
| 25MG | 672 | In Stock |
|
| 50MG | 945 | In Stock |
|
| 100MG | 1278 | In Stock |
|
| 500MG | 2547 | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
-
Product NameUNC926 hydrochloride
-
NoteResearch use only, not for human use.
-
Brief DescriptionUNC926 hydrochloride is a methyl-lysine (Kme) reader domain inhibitor.
-
DescriptionUNC926 hydrochloride is a methyl-lysine (Kme) reader domain inhibitor.
-
In VitroUNC926 also exhibits a low micromolar affinity for the close homolog, L3MBTL3 ( IC50 of 3.2 μM), with a decrease in affinity for the other MBT domains and no binding to CBX7.UNC926 (1-25 μM) inhibits binding of the 3xMBT domain to H4K20me1.UNC926 inhibits the association of L3MBTL13xMBT with the appropriate histonepeptides in a dose-dependent manner. UNC926 does not have an effect on the binding of 53BP1 to H4K20me1, demonstrating specificity of UNC926 for L3MBTL1 over 53BP1.
-
In Vivo——
-
Synonyms——
-
PathwayChromatin/Epigenetic
-
TargetEpigenetic Reader Domain
-
RecptorL3MBTL1|L3MBTL3|L3MBTL4
-
Research Area——
-
Indication——
Chemical Information
-
CAS Number1782573-49-2
-
Formula Weight373.72
-
Molecular FormulaC16H22BrClN2O
-
Purity>98% (HPLC)
-
SolubilityDMSO:150 mg/mL?(444.77 mM)
-
SMILESO=C(C1=CC=CC(Br)=C1)N2CCC(N3CCCC3)CC2.[H]Cl
-
Chemical Name——
Shipping & Storage Information
-
Storage(-20℃)
-
ShippingWith Ice Pack
-
Stability≥ 2 years
Reference
1.Herold JM, et al. Structure-activity relationships of methyl-lysine reader antagonists. MedChemComm. 2012;3(45):45-51.
molnova catalog
related products
-
Curcumin
Curcumin is a natural phenolic compound with impressive antioxidant properties. Curcumin is recently proved to exert its chemopreventive effects partly through the activation of nuclear factor (erythroid-2 related) factor 2 (Nrf2).
-
BRD7-IN-1
BRD7-IN-1, a modified derivative of BI7273 (BRD7/9 inhibitor), forms PROTAC VZ185 via linkage to a VHL ligand, demonstrating potent activity against BRD7/9 with DC50 values of 4.5 and 1.8 nM, respectively .
-
UNC926 hydrochloride
UNC926 hydrochloride is a?methyl-lysine (Kme) reader domain?inhibitor.
