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UNC2541
CAS No. 1612782-86-1
UNC2541( —— )
Catalog No. M23714 CAS No. 1612782-86-1
UNC2541 is a potent and Mer tyrosine kinase (MerTK)-specific inhibitor. It also binds in the MerTK ATP pocket (IC50: 4.4 nM).
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 2MG | 38 | In Stock |
|
| 5MG | 61 | In Stock |
|
| 10MG | 98 | In Stock |
|
| 25MG | 210 | In Stock |
|
| 50MG | 314 | In Stock |
|
| 100MG | Get Quote | In Stock |
|
| 200MG | Get Quote | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
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Product NameUNC2541
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NoteResearch use only, not for human use.
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Brief DescriptionUNC2541 is a potent and Mer tyrosine kinase (MerTK)-specific inhibitor. It also binds in the MerTK ATP pocket (IC50: 4.4 nM).
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DescriptionUNC2541 is a potent and Mer tyrosine kinase (MerTK)-specific inhibitor. It also binds in the MerTK ATP pocket (IC50: 4.4 nM). UNC2541 inhibits phosphorylated MerTK (pMerTK; EC50, 510 nM).
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In Vitro——
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In Vivo——
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Synonyms——
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PathwayTyrosine Kinase
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TargetTAM Receptor
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RecptorAxl|Flt3|pMerTK|Tyro3
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Research Area——
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Indication——
Chemical Information
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CAS Number1612782-86-1
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Formula Weight471.57
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Molecular FormulaC24H34FN7O2
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Purity>98% (HPLC)
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SolubilityDMSO:10 mg/mL (21.21 mM; ultrasonic and warming and heat to 60°C)
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SMILESC1CCCNC2=NC=C(C(=N2)NCCCC[C@@H](C(=O)NCC1)N)C(=O)NCC3=CC=C(C=C3)F
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1.McIver AL, et al. Discovery of Macrocyclic Pyrimidines as MerTK-Specific Inhibitors. ChemMedChem. 2017 Feb 3;12(3):207-213.
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