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ULK-101

CAS No. 2443816-45-1

ULK-101( —— )

Catalog No. M24125 CAS No. 2443816-45-1

ULK-101 suppresses autophagy induction and autophagic flux in response to different stimuli.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
2MG 218 In Stock
5MG 335 In Stock
10MG 537 In Stock
25MG 842 In Stock
50MG 1134 In Stock
100MG 1521 In Stock
500MG 3042 In Stock
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Biological Information

  • Product Name
    ULK-101
  • Note
    Research use only, not for human use.
  • Brief Description
    ULK-101 suppresses autophagy induction and autophagic flux in response to different stimuli.
  • Description
    ULK-101 suppresses autophagy induction and autophagic flux in response to different stimuli.
  • In Vitro
    ULK-101 (0-5 μM) reduces BafA1-induced LC3B-II accumulation in U2OS cells in a concentration-dependent manner.
  • In Vivo
    ——
  • Synonyms
    ——
  • Pathway
    Autophagy
  • Target
    Autophagy
  • Recptor
    ULK1
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    2443816-45-1
  • Formula Weight
    460.4
  • Molecular Formula
    C22H16F4N4OS
  • Purity
    >98% (HPLC)
  • Solubility
    DMSO:84mg/mL (182.43mM)
  • SMILES
    O=C(C1=CC(C2=C3N=CC(C4=CC=C(F)C=C4)=CN3N=C2)=CS1)N[C@@H](C5CC5)C(F)(F)F
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Martin KR, Celano SL, Solitro AR, et al. A Potent and Selective ULK1 Inhibitor Suppresses Autophagy and Sensitizes Cancer Cells to Nutrient Stress. iScience. 2018;8:74-84. doi:10.1016/j.isci.2018.09.012
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