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Troleandomycin
CAS No. 2751-09-9
Troleandomycin( —— )
Catalog No. M33708 CAS No. 2751-09-9
Troleandomycin (Triacetyloleandomycin), a macrolide antibiotic, is an orally active and specific CYP3A inhibitor that induces mnemonic speech, induces prolonged cholestasis, and can be used in the study of asthma.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 2MG | 758 | Get Quote |
|
| 500MG | Get Quote | Get Quote |
|
| 1G | Get Quote | Get Quote |
|
Biological Information
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Product NameTroleandomycin
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NoteResearch use only, not for human use.
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Brief DescriptionTroleandomycin (Triacetyloleandomycin), a macrolide antibiotic, is an orally active and specific CYP3A inhibitor that induces mnemonic speech, induces prolonged cholestasis, and can be used in the study of asthma.
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DescriptionTroleandomycin (Triacetyloleandomycin), a macrolide acrolide antibiotic, is a selective CYP3A inhibitor. Troleandomycin is an oral corticosteroid for asthma study.
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In Vitro——
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In VivoAnimal Model:SD female rats.Dosage:500 mg/kg.Administration:A single oral dose.Result:Markedly elevated the Cmax and AUC0-6 of simvastatin by 9.5- and 10.2-fold, respectively.
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Synonyms——
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PathwayMicrobiology/Virology
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TargetAntibiotic
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RecptorAntibiotic | P450
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Research Area——
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Indication——
Chemical Information
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CAS Number2751-09-9
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Formula Weight813.97
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Molecular FormulaC41H67NO15
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Purity>98% (HPLC)
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SolubilityIn Vitro:?DMSO : 83.33 mg/mL (102.37 mM; Ultrasonic )
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SMILES[H][C@@]1(C[C@H](OC)[C@@H](OC(C)=O)[C@H](C)O1)O[C@H]1[C@H](C)[C@@H](O[C@]2([H])O[C@H](C)C[C@@H]([C@H]2OC(C)=O)N(C)C)[C@@H](C)C[C@@]2(CO2)C(=O)[C@H](C)[C@@]([H])(OC(C)=O)[C@@H](C)[C@@H](C)OC(=O)[C@@H]1C
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Shingen Misaka, et al. Green tea extract affects the cytochrome P450 3A activity and pharmacokinetics of simvastatin in rats. Drug Metab Pharmacokinet. 2013;28(6):514-8.?
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