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Tocofersolan

CAS No. 9002-96-4

Tocofersolan( TPGS | Vitamin E-TPGS | D-α-Tocopherol polyethylene glycol 1000 succinate | Tocophersolan )

Catalog No. M19837 CAS No. 9002-96-4

Tocofersolan is a polyethylene glycol derivative of α-tocopherol and synthetic water-soluble version of Tocopherol. Tocofersolan is an oral treatment of vitamin E deficiency due to digestive malabsorption in pediatric patients with congenital chronic cholestasis or hereditary chronic cholestasis.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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Biological Information

  • Product Name
    Tocofersolan
  • Note
    Research use only, not for human use.
  • Brief Description
    Tocofersolan is a polyethylene glycol derivative of α-tocopherol and synthetic water-soluble version of Tocopherol. Tocofersolan is an oral treatment of vitamin E deficiency due to digestive malabsorption in pediatric patients with congenital chronic cholestasis or hereditary chronic cholestasis.
  • Description
    Tocofersolan is a polyethylene glycol derivative of α-tocopherol and synthetic water-soluble version of Tocopherol. Tocofersolan is an oral treatment of vitamin E deficiency due to digestive malabsorption in pediatric patients with congenital chronic cholestasis or hereditary chronic cholestasis.(In Vitro):Tocofersolan (0-3 μM) increases locomotor activity, and causes a significant attenuation of the BaP-induced hypoactivity at 1 μM in zebrafish embryos exposed to BaP.
  • In Vitro
    ——
  • In Vivo
    Tocofersolan (0-3 μM) increases locomotor activity, and causes a significant attenuation of the BaP-induced hypoactivity at 1 μM in zebrafish embryos exposed to BaP.
  • Synonyms
    TPGS | Vitamin E-TPGS | D-α-Tocopherol polyethylene glycol 1000 succinate | Tocophersolan
  • Pathway
    Others
  • Target
    Other Targets
  • Recptor
    Others
  • Research Area
    Others
  • Indication
    Vitamin deficiency

Chemical Information

  • CAS Number
    9002-96-4
  • Formula Weight
    662.942
  • Molecular Formula
    C39H66O8
  • Purity
    >98% (HPLC)
  • Solubility
    DMSO:31.25 mg/mL (54.36 mM) Need ultrasonic
  • SMILES
    ——
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Thébaut A Nemeth A Le Mouha?r J et al. Oral Tocofersolan Corrects or Prevents Vitamin E Deficiency in Children With Chronic Cholestasis[J]. Journal of Pediatric Gastroenterology & Nutrition 2016 63(6):1.
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