Thalidomide-NH-C4-NH-Boc( —— )

Catalog No. M23941 CAS No. 2093388-52-2

Thalidomide-NH-C4-NH-Boc is a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide based cereblon ligand and a linker used in PROTAC technology.

Purity : >98% (HPLC)

COA

Datasheet

HNMR

HPLC

MSDS

Handing Instructions

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Biological Information

Product Name

Thalidomide-NH-C4-NH-Boc
Note

Research use only, not for human use.
Brief Description

Thalidomide-NH-C4-NH-Boc is a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide based cereblon ligand and a linker used in PROTAC technology.
Description

Thalidomide-NH-C4-NH-Boc is a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide based cereblon ligand and a linker used in PROTAC technology.
In Vitro

——
In Vivo

——
Synonyms

——
Pathway

PROTACs
Target

E3 Ligase Ligand
Recptor

Cereblon
Research Area

——
Indication

——

Chemical Information

CAS Number

2093388-52-2
Formula Weight

444.48
Molecular Formula

C22H28N4O6
Purity

>98% (HPLC)
Solubility

DMSO:50 mg/mL (112.49 mM; Need ultrasonic)
SMILES

CC(C)(C)OC(=O)NCCCCNC1=CC=CC2=C1C(=O)N(C2=O)C3CCC(=O)NC3=O
Chemical Name

——

Shipping & Storage Information

Storage

(-20℃)
Shipping

With Ice Pack
Stability

≥ 2 years

Reference

1.Jiang F, et al.Discovery of novel small molecule induced selective degradation of the bromodomain and extra-terminal (BET) bromodomain protein BRD4 and BRD2 with cellular potencies.Bioorg Med Chem. 2020 Jan 1;28(1):115181.

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