Tetrahydrobiopterin( —— )

Catalog No. M33520 CAS No. 17528-72-2

Tetrahydrobiopterin (BH4) is a cofactor for aromatic amino acid hydroxylases and an essential cofactor for nitric oxide synthase (NOS), which is used in the study of endothelial dysfunction such as hypertension, hypercholesterolemia, and diabetes.

Purity : >98% (HPLC)

COA

Datasheet

HNMR

HPLC

MSDS

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Biological Information

Product Name

Tetrahydrobiopterin
Note

Research use only, not for human use.
Brief Description

Tetrahydrobiopterin (BH4) is a cofactor for aromatic amino acid hydroxylases and an essential cofactor for nitric oxide synthase (NOS), which is used in the study of endothelial dysfunction such as hypertension, hypercholesterolemia, and diabetes.
Description

Tetrahydrobiopterin ((Rac)-Sapropterin) is a cofactor of the aromatic amino acid hydroxylases enzymes and also acts as an essential cofactor for all nitric oxide synthase (NOS) isoforms.
In Vitro

——
In Vivo

——
Synonyms

——
Pathway

Proteasome/Ubiquitin
Target

Endogenous Metabolite
Recptor

Endogenous Metabolite | NOS
Research Area

——
Indication

——

Chemical Information

CAS Number

17528-72-2
Formula Weight

241.25
Molecular Formula

C9H15N5O3
Purity

>98% (HPLC)
Solubility

In Vitro:?DMSO : 50 mg/mL (207.25 mM; Ultrasonic )
SMILES

CC(O)C(O)C1CNc2[nH]c(N)nc(=O)c2N1
Chemical Name

——

Shipping & Storage Information

Storage

(-20℃)
Shipping

With Ice Pack
Stability

≥ 2 years

Reference

1. Rivera JC, et al. Tetrahydrobiopterin (BH4) deficiency is associated with augmented inflammation and microvascular degeneration in the retina. J Neuroinflammation. 2017 Sep 6;14(1):181.?

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