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Terbutaline

CAS No. 23031-25-6

Terbutaline( —— )

Catalog No. M22981 CAS No. 23031-25-6

Terbutaline is a short-acting agonist of β2-adrenergic receptor (β2-AR) . It is an active metabolite of bambuterol.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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Biological Information

  • Product Name
    Terbutaline
  • Note
    Research use only, not for human use.
  • Brief Description
    Terbutaline is a short-acting agonist of β2-adrenergic receptor (β2-AR) . It is an active metabolite of bambuterol.
  • Description
    Terbutaline is a short-acting agonist of β2-adrenergic receptor (β2-AR) . It is an active metabolite of bambuterol.
  • In Vitro
    Terbutaline (0-10 μM, 1 hour) enhances MKP-1 expression in activated mouse macrophages.RT-PCR Cell Line:J774 macrophages Concentration:0-10 μM Incubation Time:1 hour Result:Enhanced MKP-1 expression in J774 macrophages in a dose-dependent manner.Western Blot Analysis Cell Line:J774 macrophages Concentration:100 nM Incubation Time:1 hour Result:Reduced the phosphorylation of p38 MAPK in J774 macrophages.
  • In Vivo
    Terbutaline (intraperitoneal injection; 0.5 mg/kg; twice a day; 20 days) treatment can improve the allodynia in ob/ob mice. Animal Model:Adult male ob/ob miceDosage:0.5 mg/kg Administration:Intraperitoneal injection; 0.5 mg/kg; twice a day; 20 days Result:Reversed the mechanical allodynia in ob/ob mice.
  • Synonyms
    ——
  • Pathway
    Angiogenesis
  • Target
    Adrenergic Receptor
  • Recptor
    β2-adrenergic receptor
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    23031-25-6
  • Formula Weight
    225.3
  • Molecular Formula
    C12H19NO3
  • Purity
    >98% (HPLC)
  • Solubility
    In Vitro:?DMSO : 250 mg/mL (1109.73 mM)
  • SMILES
    OC1=CC(C(O)CNC(C)(C)C)=CC(O)=C1
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Nanna, Krogh, Sebastian, et al. Terbutaline Accumulates in Blood and Urine after Daily Therapeutic Inhalation.[J]. Medicine & Science in Sports & Exercise, 2017.
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