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TUG-469

CAS No. 1236109-67-3

TUG-469( TUG469 | TUG 469 )

Catalog No. M28019 CAS No. 1236109-67-3

TUG-469 is an effective free fatty acid 1 receptor agonist.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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5MG 37 Get Quote
10MG 59 Get Quote
25MG 112 Get Quote
50MG 177 Get Quote
100MG 299 Get Quote
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Biological Information

  • Product Name
    TUG-469
  • Note
    Research use only, not for human use.
  • Brief Description
    TUG-469 is an effective free fatty acid 1 receptor agonist.
  • Description
    TUG-469 is an effective free fatty acid 1 receptor agonist.
  • In Vitro
    TUG-469 (0-10 μM) shows efficacy to hFFA1 with a pEC50 value of 7.73.TUG-469 (10 μM) increases the insulin secretion under 10 mM glucose stimulation.TUG-469 (0-100 μM) is >200-fold selective for FFA1 over FFA4 with EC50 values of 19 nM and 4.4 μM for FFA1 and FFA4, respectively.TUG-469 (5 μM; 30 min) significantly increases insulin secretion of INS-1 cells with the presence of high glucose concentration (16.7 mM).
  • In Vivo
    TUG-469 (5 mg/kg; i.p.; 60 and 90 min after glucose administration) affects blood glucose level. Animal Model:Male NZO mice with glucose administration Dosage:5 mg/kg Administration:Intraperitoneal injection; 5 mg/kg; 60 and 90 min after glucose administration Result:Reduced the blood glucose level.
  • Synonyms
    TUG469 | TUG 469
  • Pathway
    Others
  • Target
    Other Targets
  • Recptor
    Influenza virus|neuroprotection|Antifection
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    1236109-67-3
  • Formula Weight
    345.442
  • Molecular Formula
    C23H23NO2
  • Purity
    >98% (HPLC)
  • Solubility
    In Vitro:?DMSO : 100 mg/mL (289.49 mM)
  • SMILES
    Cc1ccccc1-c1cccc(CNc2ccc(CCC(O)=O)cc2)c1
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Jung JW, et al. Isoprenylated flavonoids from the root bark of Morus alba and their hepatoprotective and neuroprotective activities. Arch Pharm Res. 2015 Nov;38(11):2066-75.
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