TPPB

CAS No. 497259-23-1

TPPB( —— )

Catalog No. M24458 CAS No. 497259-23-1

TPPB is a kinase C activator of cell-permeable benzolactam-derived protein (Ki: 11.9 nM).

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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Biological Information

  • Product Name
    TPPB
  • Note
    Research use only, not for human use.
  • Brief Description
    TPPB is a kinase C activator of cell-permeable benzolactam-derived protein (Ki: 11.9 nM).
  • Description
    TPPB is a kinase C activator of cell-permeable benzolactam-derived protein (Ki: 11.9 nM).
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    ——
  • Pathway
    Angiogenesis
  • Target
    PKC
  • Recptor
    PKC
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    497259-23-1
  • Formula Weight
    501.54
  • Molecular Formula
    C27H30F3N3O3
  • Purity
    >98% (HPLC)
  • Solubility
    DMSO:125 mg/mL (249.23 mM; Need ultrasonic)
  • SMILES
    CC(C)[C@@H](C(N[C@H](CO)C1)=O)N(C)c(cc2)c1cc2NC(/C=C/C=C/c1ccc(C(F)(F)F)cc1)=O
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Kozikowski AP, et al. New amide-bearing benzolactam-based protein kinase C modulators induce enhanced secretion of the amyloid precursor protein metabolite sAPPalpha. J Med Chem. 2003 Jan 30;46(3):364-73.
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