TNIK-IN-7

CAS No. 1417795-24-4

TNIK-IN-7( —— )

Catalog No. M37080 CAS No. 1417795-24-4

TNIK-IN-7 is a potent and selective Traf2 and Nck interacting kinase (TNIK) inhibitor (IC50: 11 nM) with antitumor activity for studying signaling and proliferation in colorectal cancer cells.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
2MG 211 In Stock
5MG 330 In Stock
10MG 503 In Stock
25MG 821 In Stock
50MG 1132 In Stock
100MG 1431 In Stock
500MG Get Quote In Stock
1G Get Quote In Stock

Biological Information

  • Product Name
    TNIK-IN-7
  • Note
    Research use only, not for human use.
  • Brief Description
    TNIK-IN-7 is a potent and selective Traf2 and Nck interacting kinase (TNIK) inhibitor (IC50: 11 nM) with antitumor activity for studying signaling and proliferation in colorectal cancer cells.
  • Description
    TNIK-IN-7 (Compound 8) is an inhibitor of Traf2 and Nck-interacting kinase (TNIK), with IC50 of 11 nM, that has antitumor activity.
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    ——
  • Pathway
    Wnt/Notch/Hedgehog
  • Target
    Wnt/beta/catenin
  • Recptor
    Wnt/beta-catenin
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    1417795-24-4
  • Formula Weight
    386.45
  • Molecular Formula
    C23H22N4O2
  • Purity
    >98% (HPLC)
  • Solubility
    ——
  • SMILES
    N#CC=1C=CC(OC)=C(C1)C=2C=CN=C(C2)NC3=CC=C(C=C3)N4CCOCC4
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Koc-Kan Ho, et al. Discovery of 4-phenyl-2-phenylaminopyridine based TNIK inhibitors. Bioorg Med Chem Lett. 2013 Jan 15;23(2):569-73.?
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