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Sandalore

CAS No. 65113-99-7

Sandalore( —— )

Catalog No. M28810 CAS No. 65113-99-7

Sandalore prolongs human hair growth by decreasing apoptosis and increasing the production of the anagen-prolonging growth factor IGF-1 in the outer root sheath. Sandalore is a selective agonist of olfactory receptor OR2AT4.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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Biological Information

  • Product Name
    Sandalore
  • Note
    Research use only, not for human use.
  • Brief Description
    Sandalore prolongs human hair growth by decreasing apoptosis and increasing the production of the anagen-prolonging growth factor IGF-1 in the outer root sheath. Sandalore is a selective agonist of olfactory receptor OR2AT4.
  • Description
    Sandalore prolongs human hair growth by decreasing apoptosis and increasing the production of the anagen-prolonging growth factor IGF-1 in the outer root sheath. Sandalore is a selective agonist of olfactory receptor OR2AT4.(In Vitro):Sandalore (500 μM) significantly reduced hair matrix keratinocyte apoptosis and retarded spontaneous hair follicle (HF) regression (catagen development) ex vivo.
  • In Vitro
    3-Campholenyl-2-butanol (500 μM; 6 days) retards spontaneous hair follicle (HF) regression (catagen development) ex vivo and significantly reduces hair matrix keratinocyte apoptosis.
  • In Vivo
    ——
  • Synonyms
    ——
  • Pathway
    Apoptosis
  • Target
    Apoptosis
  • Recptor
    GABAA
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    65113-99-7
  • Formula Weight
    210.36
  • Molecular Formula
    C14H26O
  • Purity
    >98% (HPLC)
  • Solubility
    In Vitro:?DMSO : 100 mg/mL (475.38 mM)
  • SMILES
    CC(CCC1C(C)(C)C(C)=CC1)C(C)O
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Taliani S, et al. Identification of anxiolytic/nonsedative agents among indol-3-ylglyoxylamides acting as functionally selective agonists at the gamma-aminobutyric acid-A (GABAA) alpha2 benzodiazepine receptor. J Med Chem. 2009 Jun 25;52(12):3723-34.
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