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SPDB
CAS No. 115088-06-7
SPDB( SPDB, SPDB disulfide heterobifunctional cross-linker )
Catalog No. M10531 CAS No. 115088-06-7
SPDB is a disulfide chemical linker for antibody-drug conjugates (ADCs).
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 2MG | 42 | In Stock |
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| 5MG | 77 | In Stock |
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| 10MG | 107 | In Stock |
|
| 50MG | 251 | In Stock |
|
| 100MG | 341 | In Stock |
|
| 200MG | 537 | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
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Product NameSPDB
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NoteResearch use only, not for human use.
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Brief DescriptionSPDB is a disulfide chemical linker for antibody-drug conjugates (ADCs).
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DescriptionSPDB is a disulfide chemical linker for antibody-drug conjugates (ADCs).
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In Vitro——
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In Vivo——
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SynonymsSPDB, SPDB disulfide heterobifunctional cross-linker
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PathwayAntibody Drug Conjugates (ADC)
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TargetADCs Linker/Click Chemistry
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RecptorOthers
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Research AreaOther Indications
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Indication——
Chemical Information
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CAS Number115088-06-7
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Formula Weight326.3913
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Molecular FormulaC13H14N2O4S2
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Purity>98% (HPLC)
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Solubility10 mM in DMSO
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SMILESO=C(ON1C(CCC1=O)=O)CCCSSC2=NC=CC=C2
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Chemical NameButanoic acid, 4-(2-pyridinyldithio)-, 2,5-dioxo-1-pyrrolidinyl ester
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Cumber AJ, et al. Bioconjug Chem. 1992 Sep-Oct;3(5):397-401.
2. Erickson HK, et al. Cancer Res. 2006 Apr 15;66(8):4426-33.
3. Ikeda H, et al. Clin Cancer Res. 2009 Jun 15;15(12):4028-37.
4. Zhao RY, et al. J Med Chem. 2011 May 26;54(10):3606-23.
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