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SMI-16a

CAS No. 587852-28-6

SMI-16a( Pim1/2 Inhibitor IV | PIM1/2 Kinase Inhibitor VI )

Catalog No. M17550 CAS No. 587852-28-6

PIM1/2 Kinase Inhibitor VI, a cell-permeable thiazolidinedione compound, acts as an effective, ATP-competitive inhibitor against Pim-1/2 kinases (IC50: 150/20 nM).

Purity : >98% (HPLC)

COA

Datasheet

HNMR

HPLC

MSDS

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Size	Price / USD	Stock	Quantity
2MG	36	In Stock
5MG	58	In Stock
10MG	80	In Stock
25MG	147	In Stock
50MG	222	In Stock
100MG	335	In Stock
200MG	Get Quote	In Stock
500MG	Get Quote	In Stock
1G	Get Quote	In Stock

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Biological Information

Product Name

SMI-16a
Note

Research use only, not for human use.
Brief Description

PIM1/2 Kinase Inhibitor VI, a cell-permeable thiazolidinedione compound, acts as an effective, ATP-competitive inhibitor against Pim-1/2 kinases (IC50: 150/20 nM).
Description

SMI-16a, also known as Pim1/2 Inhibitor IV, is a potent, cell-permeable, ATP-competitive inhibitor of Pim-1/2 kinases (IC50 = 150 nM and 20 nM against Pim-1 and Pim-2, respectively).
In Vitro

——
In Vivo

——
Synonyms

Pim1/2 Inhibitor IV | PIM1/2 Kinase Inhibitor VI
Pathway

GPCR/G Protein
Target

GPCR19
Recptor

Pim1| Pim2
Research Area

Cancer
Indication

——

Chemical Information

CAS Number

587852-28-6
Formula Weight

263.31
Molecular Formula

C13H13NO3S
Purity

>98% (HPLC)
Solubility

DMSO : ≥ 150 mg/mL; 569.67 mM
SMILES

CCCOC1=CC=C(C=C1)/C=C\2/C(=O)NC(=O)S2
Chemical Name

(Z)-5-(4-Propoxybenzylidene)thiazolidine-2,4-dione

Shipping & Storage Information

Storage

(-20℃)
Shipping

With Ice Pack
Stability

≥ 2 years

Reference

1. Xia Z., et al. Synthesis and evaluation of novel inhibitors of Pim-1 and Pim-2 protein kinases. J Med Chem. 2009 Jan 8;52(1):74-86.

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