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SMI-16a
CAS No. 587852-28-6
SMI-16a( Pim1/2 Inhibitor IV | PIM1/2 Kinase Inhibitor VI )
Catalog No. M17550 CAS No. 587852-28-6
PIM1/2 Kinase Inhibitor VI, a cell-permeable thiazolidinedione compound, acts as an effective, ATP-competitive inhibitor against Pim-1/2 kinases (IC50: 150/20 nM).
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 2MG | 36 | In Stock |
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| 5MG | 58 | In Stock |
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| 10MG | 80 | In Stock |
|
| 25MG | 147 | In Stock |
|
| 50MG | 222 | In Stock |
|
| 100MG | 335 | In Stock |
|
| 200MG | Get Quote | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
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Product NameSMI-16a
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NoteResearch use only, not for human use.
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Brief DescriptionPIM1/2 Kinase Inhibitor VI, a cell-permeable thiazolidinedione compound, acts as an effective, ATP-competitive inhibitor against Pim-1/2 kinases (IC50: 150/20 nM).
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DescriptionSMI-16a, also known as Pim1/2 Inhibitor IV, is a potent, cell-permeable, ATP-competitive inhibitor of Pim-1/2 kinases (IC50 = 150 nM and 20 nM against Pim-1 and Pim-2, respectively).
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In Vitro——
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In Vivo——
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SynonymsPim1/2 Inhibitor IV | PIM1/2 Kinase Inhibitor VI
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PathwayGPCR/G Protein
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TargetGPCR19
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RecptorPim1| Pim2
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Research AreaCancer
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Indication——
Chemical Information
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CAS Number587852-28-6
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Formula Weight263.31
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Molecular FormulaC13H13NO3S
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Purity>98% (HPLC)
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SolubilityDMSO : ≥ 150 mg/mL; 569.67 mM
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SMILESCCCOC1=CC=C(C=C1)/C=C\2/C(=O)NC(=O)S2
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Chemical Name(Z)-5-(4-Propoxybenzylidene)thiazolidine-2,4-dione
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Xia Z., et al. Synthesis and evaluation of novel inhibitors of Pim-1 and Pim-2 protein kinases. J Med Chem. 2009 Jan 8;52(1):74-86.
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