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SLC26A3-IN-1
CAS No. 307552-53-0
SLC26A3-IN-1( —— )
Catalog No. M36419 CAS No. 307552-53-0
SLC26A3-IN-1 is an inhibitor of the anion-exchange protein SLC26A3 with an IC50 value of 340 nM. SLC26A3, a solute carrier (SLC) protein and member of the SLC26 family, exhibits a wide range of anionic specificities for chloride, bicarbonate, sulfate, and oxalate.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 2MG | 296 | Get Quote |
|
| 5MG | 409 | Get Quote |
|
| 10MG | 604 | Get Quote |
|
| 25MG | 908 | Get Quote |
|
| 50MG | 1251 | Get Quote |
|
| 100MG | 1647 | Get Quote |
|
| 500MG | 3312 | Get Quote |
|
| 1G | Get Quote | Get Quote |
|
Biological Information
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Product NameSLC26A3-IN-1
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NoteResearch use only, not for human use.
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Brief DescriptionSLC26A3-IN-1 is an inhibitor of the anion-exchange protein SLC26A3 with an IC50 value of 340 nM. SLC26A3, a solute carrier (SLC) protein and member of the SLC26 family, exhibits a wide range of anionic specificities for chloride, bicarbonate, sulfate, and oxalate.
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DescriptionSLC26A3-IN-1 is an inhibitor of anion exchanger protein SLC26A3 (IC50=340 nM). SLC26A3 belongs to solute carrier (SLC) proteins, and the SLC26 family. SLC26 family has broad anion specificity for chloride, bicarbonate, sulfate and oxalate. SLC26A3 down-regulates in adenoma, DRA, involves in in intestinal absorption of chloride and oxalate. The loss of SLC26A3 function mutations is associated with chloride-losing diarrhea.
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In Vitro——
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In Vivo——
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Synonyms——
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PathwayOthers
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TargetOther Targets
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Recptortransporter
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Research Area——
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Indication——
Chemical Information
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CAS Number307552-53-0
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Formula Weight358.39
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Molecular FormulaC23H18O4
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Purity>98% (HPLC)
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Solubility——
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SMILESC(O)(=O)C=1C=2C(OC1C3=CC=CC=C3)=CC=C(OCC4=C(C)C=CC=C4)C2
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Cil O, et al. Small molecule inhibitors of intestinal epithelial anion exchanger SLC26A3 (DRA) with a luminal, extracellular site of action. Eur J Med Chem. 2023 Mar 5;249:115149.?
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