Euscaphic acid has anti-diabetic, and anti-inflammatory activities, it inhibits LPS-induced inflammatory responses by interference with the clustering of TRAF6 with IRAK1 and TAK1, resulting in blocking the activation of IKK and MAPKs signal transduction to downregulate NF-κB activations.

Dehydroeburicoic acid induces necrotic cell death that involves Ca(2+) overload mitochondrial dysfunction and calpain activation in human glioblastomas.

2-Iminobiotin is a cyclic guanidino analog of biotin that acts as a reversible inhibitor of inducible nitric oxide synthase (iNOS) and neuronal NOS (nNOS;?Ki of 21.8 and 37.5 μM for mouse iNOS and rat nNOS respectively).