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S107

CAS No. 927871-76-9

S107( —— )

Catalog No. M17667 CAS No. 927871-76-9

S107 is a RyR-selective 1, 4-benzothiazepine derivative that stabilizes RyR2 channels by enhancing the binding affinity of calstabin2 to mutant and/or PKA-phosphorylated channels.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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Biological Information

  • Product Name
    S107
  • Note
    Research use only, not for human use.
  • Brief Description
    S107 is a RyR-selective 1, 4-benzothiazepine derivative that stabilizes RyR2 channels by enhancing the binding affinity of calstabin2 to mutant and/or PKA-phosphorylated channels.
  • Description
    S107 is a RyR-selective 1, 4-benzothiazepine derivative that stabilizes RyR2 channels by enhancing the binding affinity of calstabin2 to mutant and/or PKA-phosphorylated channels.
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    ——
  • Pathway
    Others
  • Target
    Other Targets
  • Recptor
    Others
  • Research Area
    Cardiovascular Disease
  • Indication
    ——

Chemical Information

  • CAS Number
    927871-76-9
  • Formula Weight
    209.31
  • Molecular Formula
    C11H15NOS
  • Purity
    >98% (HPLC)
  • Solubility
    DMSO : ≥ 38 mg/mL; 181.55 mM
  • SMILES
    CN1CCSc2c(C1)cc(cc2)OC
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Lehnart SE, et al. J Clin Invest. 2008 Jun;118(6):2230-45.
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