Rhapontigenin

Research use only, not for human use.

Rhapontigenin is a mechanism-based, selective inactivator of cytochrome P450 1A1 (IC50: 400 nM), an aryl hydrocarbon hydroxylase which activates polycyclic aromatic hydrocarbons that act as procarcinogens.

Rhapontigenin is a mechanism-based, selective inactivator of cytochrome P450 1A1 (IC50: 400 nM), an aryl hydrocarbon hydroxylase which activates polycyclic aromatic hydrocarbons that act as procarcinogens. Rhapontigenin is a natural analog of resveratrol with antioxidant and anti-cancer activity. ?At higher concentrations, rhapontigenin inhibits the proliferation of HL-60R and HepG2 cancer cell lines (IC50: 48 μM).

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Animal Model:ICR mice Dosage:25mg/kg Administration:25mg/kg; intraperitoneal injection Result:Showed anti-thrombosis activity with 60% protection.

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Endocrinology/Hormones

AChR

CYP1A1

Others-Field

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500-65-2

258.3

C15H14O4

>98% (HPLC)

In Vitro:?DMSO : 125 mg/mL (483.99 mM)

COc1c(cc(cc1)/C=C/c1cc(cc(c1)O)O)O

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(-20℃)

With Ice Pack

≥ 2 years