Repertaxin
CAS No. 266359-83-5
Repertaxin( Repertaxin | DF 1681Y )
Catalog No. M17461 CAS No. 266359-83-5
Reparixin is a potent inhibitor of both CXCL8 receptors?CXCR1/2, it inhibits weakly?CXCR2-mediated cell migration (IC50=100 nM), whereas it strongly blocks?CXCR1-mediated chemotaxis (IC50=1 nM).
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 2MG | 65 | In Stock |
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| 5MG | 110 | In Stock |
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| 10MG | 177 | In Stock |
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| 25MG | 372 | In Stock |
|
| 50MG | 556 | In Stock |
|
| 100MG | 791 | In Stock |
|
| 500MG | 1575 | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
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Product NameRepertaxin
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NoteResearch use only, not for human use.
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Brief DescriptionReparixin is a potent inhibitor of both CXCL8 receptors?CXCR1/2, it inhibits weakly?CXCR2-mediated cell migration (IC50=100 nM), whereas it strongly blocks?CXCR1-mediated chemotaxis (IC50=1 nM).
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DescriptionReparixin is a potent inhibitor of both CXCL8 receptors?CXCR1/2, it inhibits weakly?CXCR2-mediated cell migration (IC50=100 nM), whereas it strongly blocks?CXCR1-mediated chemotaxis (IC50=1 nM).
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In Vitro——
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In Vivo——
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SynonymsRepertaxin | DF 1681Y
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PathwayGPCR/G Protein
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TargetCannabinoid Receptor
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RecptorCXCR1| CXCR2
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Research AreaInflammation/Immunology
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Indication——
Chemical Information
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CAS Number266359-83-5
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Formula Weight283.39
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Molecular FormulaC14H21NO3S
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Purity>98% (HPLC)
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SolubilityDMSO : ≥ 500 mg/mL; 1764.35 mM
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SMILESCS(=O)(=O)NC(=O)[C@@H](c1ccc(CC(C)C)cc1)C
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1.Moriconi A, et al. Design of noncompetitive interleukin-8 inhibitors acting on CXCR1 and CXCR2. J Med Chem. 2007 Aug 23;50(17):3984-4002.
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