RMC-9805( —— )

Catalog No. M37155 CAS No. 2922732-54-3

RMC-9805 is a potent KRAS G12D inhibitor with potential anti-tumor and inhibitory activity against tumor cell proliferation for the study of pancreatic cancer.

Purity : >98% (HPLC)

COA

Datasheet

HNMR

HPLC

MSDS

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5MG	312	Get Quote
10MG	534	Get Quote
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Biological Information

Product Name

RMC-9805
Note

Research use only, not for human use.
Brief Description

RMC-9805 is a potent KRAS G12D inhibitor with potential anti-tumor and inhibitory activity against tumor cell proliferation for the study of pancreatic cancer.
Description

KRAS G12D inhibitor 18 is a potent KRAS G12D inhibitor.
In Vitro

——
In Vivo

——
Synonyms

——
Pathway

Others
Target

Other Targets
Recptor

Kras
Research Area

——
Indication

——

Chemical Information

CAS Number

2922732-54-3
Formula Weight

1168.44
Molecular Formula

C63H88F3N11O7
Purity

>98% (HPLC)
Solubility

In Vitro:?DMSO : 125 mg/mL (106.98 mM; Ultrasonic )
SMILES

C(C(F)(F)F)N1C(=C2C=3C1=CC=C(C3)N4C[C@](C[C@H](NC([C@@H](N5C[C@@]6(CC5)CN(C(=O)[C@H]7[C@H](N7C)[C@@H]8CC8)CC6)[C@H]9CCCC9)=O)C(=O)N%10N[C@](C(=O)OCC(C)(C)C2)(CCC%10)[H])(OCC4)[H])C%11=C([C@@H](OC)C)N=CC(=C%11)N%12CCN(CC%12)C%13CC%13
Chemical Name

——

Shipping & Storage Information

Storage

(-20℃)
Shipping

With Ice Pack
Stability

≥ 2 years

Reference

1. BLAKE JAMES F, et al. Preparation of peptide-linked macrocyclic dipeptides as Ras inhibitors.World Intellectual Property Organization, WO2023060253 A1 2023-04-13

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