Qstatin

CAS No. 902688-24-8

Qstatin( —— )

Catalog No. M20499 CAS No. 902688-24-8

QStatin a Selective Inhibitor of Quorum Sensing in?Vibrio?Species( SmcR with an EC50 of 208.9 nM).

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
2MG 43 In Stock
5MG 72 In Stock
10MG 132 In Stock
25MG 213 In Stock
50MG 295 In Stock
100MG 484 In Stock
200MG Get Quote In Stock
500MG Get Quote In Stock
1G Get Quote In Stock

Biological Information

  • Product Name
    Qstatin
  • Note
    Research use only, not for human use.
  • Brief Description
    QStatin a Selective Inhibitor of Quorum Sensing in?Vibrio?Species( SmcR with an EC50 of 208.9 nM).
  • Description
    QStatin a Selective Inhibitor of Quorum Sensing in?Vibrio?Species( SmcR with an EC50 of 208.9 nM).
  • In Vitro
    QStatin (0.001 μM-10 μM; 5 hours) inhibits SmcR activity measured by the RLU level for V. vulnificusWT (pBB1), reveals EC50 of 208.9 nM.QStatin (5 μM-50 μM; 16 hours) reduces the activities of SmcR-activated virulence factors (protease and elastase) in V. vulnificus in a dose dependent manner. QStatin (5 μM-50 μM; 16 hours) has no effect on the cellular levels of SmcR, indicating that QStatin does not affect the expression or stability of SmcR.
  • In Vivo
    ——
  • Synonyms
    ——
  • Pathway
    GPCR/G Protein
  • Target
    Antibacterial
  • Recptor
    SmcR
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    902688-24-8
  • Formula Weight
    293.16
  • Molecular Formula
    C7H5BrN2O2S2
  • Purity
    >98% (HPLC)
  • Solubility
    DMSO:83.33 mg/mL (284.25 mM)
  • SMILES
    Brc1ccc(s1)S(=O)(=O)n1cccn1
  • Chemical Name
    1-(5-Bromothiophene-2-sulfonyl)-1H-pyrazole

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Kim B S Jang S Y Bang Y J et al. QStatin a Selective Inhibitor of Quorum Sensing in Vibrio Species[J]. mBio 2018 9(1).
molnova catalog
related products
  • Crebanine

    Crebanine iv 5mg/kg can eonvert BaCl_2-induced arrhythmia into sinus rhythm in rats, and can significantly increase the tolerant dose of aconitine to produce ventrieular fibrillation(VF) and cardiac arrest (CA) in rata.

  • Iclaprim

    Iclaprim is a novel specific bacterial Dihydrofolate inhibitor.

  • GSK2556286

    GSK2556286 (GSK286) is an orally active inhibitor of Mycobacterium tuberculosis (M. tuberculosis), effective against multidrug-resistant (MDR), extensively drug-resistant (XDR), and drug-sensitive (DS) strains.