Phentolamine

Research use only, not for human use.

Phentolamine mesylate is an alpha-1 and alpha-2 selective adrenergic receptor antagonist.

Phentolamine mesylate is an alpha-1 and alpha-2 selective adrenergic receptor antagonist.

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Phentolamine (5-20 mg/kg; i.p.) effectively inhibits the seizures elicited by strychnine (2 mg/kg, i.p.) and attenuates the seizure-potentiating effect of DOPS (4 mg/kg, i.p.) in mouse.Phentolamine (1 mg/kg; i.p.) increases insulin secretion by inhibition of b-cell a2A-adrenoceptors in mouse. Animal Model:WT miceDosage:1 mg/kg Administration:IP Result:Reduced blood glucose and increased insulin levels.

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Angiogenesis

Adrenergic Receptor

α1-adrenergic receptor|α2-adrenergic receptor

Others

Decrease in Night VisionDisturbance

50-60-2

281.36

C17H19N3O

>98% (HPLC)

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Cc1ccc(cc1)N(CC1=NCCN1)c1cccc(O)c1

Phenol 3-(((45-dihydro-1H-imidazol-2-yl)methyl)(4-methylphenyl)amino)-

(-20℃)

With Ice Pack

≥ 2 years