PKC-IN-7

CAS No. 860468-10-6

PKC-IN-7( —— )

Catalog No. M16235 CAS No. 860468-10-6

PKC-IN-7 is a potent, selective, reversible, ATP-competitive PKCα/β inhibitor with IC50 of 4.7/3.3 nM.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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Biological Information

  • Product Name
    PKC-IN-7
  • Note
    Research use only, not for human use.
  • Brief Description
    PKC-IN-7 is a potent, selective, reversible, ATP-competitive PKCα/β inhibitor with IC50 of 4.7/3.3 nM.
  • Description
    PKC-IN-7 is a potent, selective, reversible, ATP-competitive PKCα/β inhibitor with IC50 of 4.7/3.3 nM; dispalys >50-fold selectivity against PKC isotypes δ,ε,η,θ and other kinases belonging to the AGC family; inhibits IgM-stimulated mouse B cell proliferation with an IC50 of 296 nM.
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    ——
  • Pathway
    Angiogenesis
  • Target
    PKC
  • Recptor
    PKC
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    860468-10-6
  • Formula Weight
    443.931
  • Molecular Formula
    C26H22ClN3O2
  • Purity
    >98% (HPLC)
  • Solubility
    ——
  • SMILES
    ——
  • Chemical Name
    3-(2-chloro-7-((dimethylamino)methyl)naphthalen-1-yl)-4-(1-methyl-1H-indol-3-yl)-1H-pyrrole-2,5-dione

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. van Eis MJ, et al. Bioorg Med Chem Lett. 2017 Feb 15;27(4):781-786.
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