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PDD00017273
CAS No. 1945950-21-9
PDD00017273( —— )
Catalog No. M35296 CAS No. 1945950-21-9
PDD00017273 is a radiosensitizing PARG) inhibitor with antitumor or activity for the study of epithelial ovaries.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 5MG | 71 | Get Quote |
|
| 10MG | 132 | Get Quote |
|
| 25MG | 274 | Get Quote |
|
| 50MG | 411 | Get Quote |
|
| 100MG | 581 | Get Quote |
|
| 500MG | 1197 | Get Quote |
|
| 1G | Get Quote | Get Quote |
|
Biological Information
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Product NamePDD00017273
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NoteResearch use only, not for human use.
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Brief DescriptionPDD00017273 is a radiosensitizing PARG) inhibitor with antitumor or activity for the study of epithelial ovaries.
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DescriptionPDD 00017273 is a potent inhibitor of Poly(ADP-ribose) Glycohydrolase (PARG), with an IC50 of 26 nM, and a KD of 1.45 nM.
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In Vitro——
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In Vivo——
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Synonyms——
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PathwayOthers
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TargetOther Targets
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RecptorOthers
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Research Area——
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Indication——
Chemical Information
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CAS Number1945950-21-9
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Formula Weight514.62
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Molecular FormulaC23H26N6O4S2
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Purity>98% (HPLC)
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SolubilityIn Vitro:?DMSO : 25 mg/mL (48.58 mM; Ultrasonic (<60°C)
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SMILESCc1cc(Cn2c3ccc(cc3c(=O)n(Cc3cnc(C)s3)c2=O)S(=O)(=O)NC2(C)CC2)n(C)n1
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. James DI, et al. First-in-Class Chemical Probes against Poly(ADP-ribose) Glycohydrolase (PARG) Inhibit DNA Repair with Differential Pharmacology to AZD2281. ACS Chem Biol. 2016 Nov 18;11(11):3179-3190. Epub 2016 Oct 12.?
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