Orellanine( 2-(1,3-dihydroxy-4-oxopyridin-2-yl)-1,3-dihydroxypyridin-4-one )

Catalog No. M28005 CAS No. 37338-80-0

Orellanine is a nephrotoxic compound extracted from the mushroom Cortinarius orellanus.

Purity : >98% (HPLC)

COA

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Biological Information

Product Name

Orellanine
Note

Research use only, not for human use.
Brief Description

Orellanine is a nephrotoxic compound extracted from the mushroom Cortinarius orellanus.
Description

Orellanine is a nephrotoxic compound extracted from the mushroom Cortinarius orellanus. Orellanine strongly inhibits the synthesis of macromolecules (Proteins, RNA and DNA) in Madin-Darby canine kidney cells and in rat liver mitochondria.
In Vitro

——
In Vivo

——
Synonyms

2-(1,3-dihydroxy-4-oxopyridin-2-yl)-1,3-dihydroxypyridin-4-one
Pathway

Others
Target

Other Targets
Recptor

bradykinin B1
Research Area

——
Indication

——

Chemical Information

CAS Number

37338-80-0
Formula Weight

252.182
Molecular Formula

C10H8N2O6
Purity

>98% (HPLC)
Solubility

——
SMILES

Oc1cc[n+]([O-])c(c1O)-c1c(O)c(O)cc[n+]1[O-]
Chemical Name

——

Shipping & Storage Information

Storage

(-20℃)
Shipping

With Ice Pack
Stability

≥ 2 years

Reference

1.Leeb-Lundberg LM, et al. International union of pharmacology. XLV. Classification of the kinin receptor family: from molecular mechanisms to pathophysiological consequences. Pharmacol Rev. 2005 Mar;57(1):27-77.

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