O-Nornuciferine( —— )

Catalog No. M24249 CAS No. 3153-55-7

O-Nornuciferine reveals distinct in vitro hERG blockages measured in HEK293 cells with the IC50 value of 2.89 uM.

Purity : >98% (HPLC)

COA

Datasheet

HNMR

HPLC

MSDS

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Biological Information

Product Name

O-Nornuciferine
Note

Research use only, not for human use.
Brief Description

O-Nornuciferine reveals distinct in vitro hERG blockages measured in HEK293 cells with the IC50 value of 2.89 uM.
Description

O-Nornuciferine reveals distinct in vitro hERG blockages measured in HEK293 cells with the IC50 value of 2.89 uM.
In Vitro

O-Nornuciferine has an IC50 of 7.91 μM in vitro hERG blockages measured in HEK293 cells. O-Nornuciferine (100 μM) has 47% hERG channel inhibition in Xenopus oocytes by lotus alkaloids.
In Vivo

——
Synonyms

——
Pathway

Angiogenesis
Target

EGFR
Recptor

hERG
Research Area

——
Indication

——

Chemical Information

CAS Number

3153-55-7
Formula Weight

281.35
Molecular Formula

C18H19NO2
Purity

>98% (HPLC)
Solubility

In Vitro:?DMSO : 50 mg/mL (177.71 mM)
SMILES

CN(CC1)[C@H](Cc(cccc2)c2-c2c3OC)c2c1cc3O
Chemical Name

——

Shipping & Storage Information

Storage

(-20℃)
Shipping

With Ice Pack
Stability

≥ 2 years

Reference

1.Human Ether-??-go-go Related Gene (hERG) Channel Blocking Aporphine Alkaloids from Lotus Leaves and Their Quantitative Analysis in Dietary Weight Loss Supplements.J Agric Food Chem. 2015 Jun 17;63(23):5634-9.

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