A cell-permeable synthetic peptide NEMO-binding domain peptide (NBD peptide) corresponding to the NEMO amino-terminal alpha-helical region is shown to block TNF-alpha-induced NF-kB activation. The interaction of IKγNEMO with the IKK complex is vital for the activation of the IKK complex and the subsequent activation of NF-kB.

An orally active, selective and potent Glucosylceramide synthase (GCS) inhibitor with central nervous system (CNS) access.

Indole-3-pyruvic Acid is a compound involved in the biosynthesis of Indole-3-acetic acid a plant hormone which plays important roles in regulating growth and responses to environmental changes.