Neotuberostemonine

CAS No. 143120-46-1

Neotuberostemonine( —— )

Catalog No. M19780 CAS No. 143120-46-1

Neotuberostemonine (NTS) is one of the main antitussive alkaloids in the root of Stemona tuberosa Lour it has a significant protective effect on bleomycin (BLM)-induced pulmonary fibrosis through suppressing the recruitment and M2 polarization of macrophages. Neotuberostemonine demonstrates antitussive properties in guinea pigs.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
5MG 200 In Stock
10MG 295 In Stock
25MG 498 In Stock
50MG 710 In Stock
100MG 963 In Stock
200MG Get Quote In Stock
500MG Get Quote In Stock
1G Get Quote In Stock

Biological Information

  • Product Name
    Neotuberostemonine
  • Note
    Research use only, not for human use.
  • Brief Description
    Neotuberostemonine (NTS) is one of the main antitussive alkaloids in the root of Stemona tuberosa Lour it has a significant protective effect on bleomycin (BLM)-induced pulmonary fibrosis through suppressing the recruitment and M2 polarization of macrophages. Neotuberostemonine demonstrates antitussive properties in guinea pigs.
  • Description
    Neotuberostemonine (NTS) is one of the main antitussive alkaloids in the root of Stemona tuberosa Lour it has a significant protective effect on bleomycin (BLM)-induced pulmonary fibrosis through suppressing the recruitment and M2 polarization of macrophages. Neotuberostemonine demonstrates antitussive properties in guinea pigs.
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    ——
  • Pathway
    Immunology/Inflammation
  • Target
    NOS
  • Recptor
    NOS
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    143120-46-1
  • Formula Weight
    375.5
  • Molecular Formula
    C22H33NO4
  • Purity
    >98% (HPLC)
  • Solubility
    DMSO:10 mM
  • SMILES
    CC[C@H]1[C@H]2OC(=O)[C@@H](C)[C@H]2[C@@H]2C[C@@H]([C@@H]3C[C@H](C)C(=O)O3)N3CCCC[C@H]1[C@H]23
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Xiang J Cheng S Feng T et al. Neotuberostemonine attenuates bleomycin-induced pulmonary fibrosis by suppressing the recruitment and activation of macrophages[J]. International Immunopharmacology 2016 36:158-164.
molnova catalog
related products
  • Nitroarginine

    Nitroarginine is a competitive inhibitor of nitric oxide synthase which causes the selective reduction of blood flow to tumor cells.

  • Resveratroloside

    Resveratroloside has cardioprotective effect, it exhibits α±-glucosidase inhibitory activity, it also can inhibit hydroxylation of testosterone by CYP3A4.

  • ETHYL CAFFEATE b

    In vitro ECF suppressed the differentiation of naive CD4+ T cells into Th1. Furthermore ECF intensely blocked the transcriptional expression in interferon-γ-related signaling including IFN-γ T-bet STAT1 and STAT4.?