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NP-G2-044

CAS No. 1807454-59-6

NP-G2-044( —— )

Catalog No. M23818 CAS No. 1807454-59-6

NP-G2-044 is an orally active fascin inhibitor, with an IC50 of ~2 μM. It blocks tumor metastasis and increases antitumor immune response.

Purity : >98% (HPLC)

COA

Datasheet

HNMR

HPLC

MSDS

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Size	Price / USD	Stock	Quantity
2MG	61	In Stock
5MG	91	In Stock
10MG	135	In Stock
25MG	281	In Stock
50MG	426	In Stock
100MG	624	In Stock
500MG	1314	In Stock
1G	Get Quote	In Stock

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Biological Information

Product Name

NP-G2-044
Note

Research use only, not for human use.
Brief Description

NP-G2-044 is an orally active fascin inhibitor, with an IC50 of ~2 μM. It blocks tumor metastasis and increases antitumor immune response.
Description

NP-G2-044 is an orally active fascin inhibitor, with an IC50 of ~2 μM. It blocks tumor metastasis and increases antitumor immune response.
In Vitro

——
In Vivo

Animal Model:6-8 week old female BALB/c mice (mouse model bearing 4T1 tumor cells) Dosage:100 mg/kg Administration:I.p.; daily for 18 days Result:Inhibition of 4T1 mouse mammary tumor cell metastasis to the lung.
Synonyms

——
Pathway

Others
Target

Other Targets
Recptor

fascin
Research Area

——
Indication

——

Chemical Information

CAS Number

1807454-59-6
Formula Weight

399.37
Molecular Formula

C21H16F3N3O2
Purity

>98% (HPLC)
Solubility

DMSO:100 mg/mL (250.39 mM; Need ultrasonic)
SMILES

Cc(occ1)c1C(Nc1nn(Cc2ccc(C(F)(F)F)cc2)c2c1cccc2)=O
Chemical Name

——

Shipping & Storage Information

Storage

(-20℃)
Shipping

With Ice Pack
Stability

≥ 2 years

Reference

1.Han S, et al. Improving fascin inhibitors to block tumor cell migration and metastasis. Mol Oncol. 2016;10(7):966-980.

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