NOS1-IN-1

CAS No. 357965-99-2

NOS1-IN-1( —— )

Catalog No. M34975 CAS No. 357965-99-2

NOS1-IN-1(nNOS Inhibitor I) is a potent, selective and cell permeable nNOS inhibitor (Ki: 120 nM).

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
2MG 161 Get Quote
5MG 221 Get Quote
10MG 333 Get Quote
25MG 547 Get Quote
50MG 811 Get Quote
100MG 1071 Get Quote
500MG Get Quote Get Quote
1G Get Quote Get Quote

Biological Information

  • Product Name
    NOS1-IN-1
  • Note
    Research use only, not for human use.
  • Brief Description
    NOS1-IN-1(nNOS Inhibitor I) is a potent, selective and cell permeable nNOS inhibitor (Ki: 120 nM).
  • Description
    NOS1-IN-1 is a selective and cell-permeable nNOS inhibitor with a Ki of 120 nM. NOS1-IN-1 exhibits 2617-fold and 325-fold selectivity over eNOS (Ki=39 μM) and iNOS (Ki=325 μM) , respectively. NOS1-IN-1 can be used for the research of neurological disease, including cerebral palsy (CP).
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    ——
  • Pathway
    Immunology/Inflammation
  • Target
    NOS
  • Recptor
    NOS
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    357965-99-2
  • Formula Weight
    589.37
  • Molecular Formula
    C14H24F9N7O8
  • Purity
    >98% (HPLC)
  • Solubility
    ——
  • SMILES
    OC(C(F)(F)F)=O.NCCNC[C@@H](N)CCCNC(N[N+]([O-])=O)=N.OC(C(F)(F)F)=O.OC(C(F)(F)F)=O
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. J M Hah, et al. Reduced amide bond peptidomimetics. (4S)-N-(4-amino-5-[aminoakyl]aminopentyl)-N'-nitroguanidines, potent and highly selective inhibitors of neuronal nitric oxide synthase. J Med Chem. 2001 Aug 2;44(16):2667-70.?
molnova catalog
related products
  • 3-Bromo-7-Nitroindaz...

    3-Bromo-7-Nitroindazole is a more potent inhibitor of nNOS than 7-nitroindazole in vitro.

  • 3,4-O-Isopropylidene...

    3,4-Oxo- isopropylidene-shikimic acid has significant anti-inflammatory, anti-thrombosis, antioxidant, analgesic effects, it has protective effects on experimental colitis induced by trinitrobenzenesulfonic acid in rats, probably due to antioxidant action.

  • IC-87201

    A small molecule inhibitor of PSD-95/nNOS interaction with IC50 of 31 uM.