NH-bis(PEG3-azide)

Research use only, not for human use.

NH-bis(PEG3-azide) is a PROTAC linker of the PEG class used in the synthesis of PROTAC molecules.

NH-bis(PEG3-azide) is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. NH-bis(PEG3-azide) is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. Strain-promoted alkyne-azide cycloaddition (SPAAC) can also occur with molecules containing DBCO or BCN groups.

PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.

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Others

Other Targets

Others

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1258939-39-7

419.48

C16H33N7O6

>98% (HPLC)

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[N-]=[N+]=NCCOCCOCCOCCNCCOCCOCCOCCN=[N+]=[N-]

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(-20℃)

With Ice Pack

≥ 2 years