NCGC00229600

CAS No. 1338824-20-6

NCGC00229600( —— )

Catalog No. M26326 CAS No. 1338824-20-6

NCGC00229600 is an allosteric inverse thyrotropin receptor (TSHR) agonist.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
5MG 282 Get Quote
10MG 447 Get Quote
25MG 714 Get Quote
50MG 1017 Get Quote
100MG 1368 Get Quote
500MG 2673 Get Quote
1G Get Quote Get Quote

Biological Information

  • Product Name
    NCGC00229600
  • Note
    Research use only, not for human use.
  • Brief Description
    NCGC00229600 is an allosteric inverse thyrotropin receptor (TSHR) agonist.
  • Description
    NCGC00229600 is an allosteric inverse thyrotropin receptor (TSHR) agonist. NCGC00229600 inhibits both TSH and stimulating antibody activation of TSHRs endogenously and can be used in Graves' disease studies.
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    ——
  • Pathway
    Others
  • Target
    Other Targets
  • Recptor
    NF-κB
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    1338824-20-6
  • Formula Weight
    479.58
  • Molecular Formula
    C30H29N3O3
  • Purity
    >98% (HPLC)
  • Solubility
    In Vitro:?DMSO : 50 mg/mL (104.26 mM)
  • SMILES
    COc1ccc(cc1COc1c(C)cccc1C)C1Nc2ccccc2C(=O)N1Cc1cccnc1
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Neelakantan S, et al. Aminoparthenolides as novel anti-leukemic agents: Discovery of the NF-kappaB inhibitor, DMAPT (LC-1). Bioorg Med Chem Lett. 2009 Aug 1;19(15):4346-9.
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