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NCD-38
CAS No. 2078047-42-2
NCD-38( NCD38 | NCD 38 )
Catalog No. M13229 CAS No. 2078047-42-2
NCD-38 is a novel potent, selective LSD1 inhibitor with IC50 of 0.59 uM, exerts highly selective inhibitory activity on LSD1 but no other enzymes.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 5MG | 751 | In Stock |
|
| 10MG | 1064 | In Stock |
|
| 25MG | 1587 | In Stock |
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| 50MG | 2027 | In Stock |
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| 100MG | 2604 | In Stock |
|
| 200MG | Get Quote | In Stock |
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| 500MG | Get Quote | In Stock |
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| 1G | Get Quote | In Stock |
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Biological Information
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Product NameNCD-38
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NoteResearch use only, not for human use.
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Brief DescriptionNCD-38 is a novel potent, selective LSD1 inhibitor with IC50 of 0.59 uM, exerts highly selective inhibitory activity on LSD1 but no other enzymes.
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DescriptionNCD-38 is a novel potent, selective LSD1 inhibitor with IC50 of 0.59 uM, exerts highly selective inhibitory activity on LSD1 but no other enzymes, such as MAO (IC50>100 uM); inhibits the growth of MLL-AF9 leukemia as well as erythroleukemia, megakaryoblastic leukemia and myelodysplastic syndromes (MDSs) overt leukemia cells.
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In Vitro——
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In Vivo——
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SynonymsNCD38 | NCD 38
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PathwayChromatin/Epigenetic
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TargetHistone Demethylase
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RecptorHistone Demethylase
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Research Area——
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Indication——
Chemical Information
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CAS Number2078047-42-2
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Formula Weight680.165
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Molecular FormulaC37H37ClF3N3O4
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Purity>98% (HPLC)
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Solubility——
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SMILESO=C(C1=CC=C(C2=CC=CC=C2)C=C1)N[C@H](C(NCC3=CC=CC(Cl)=C3)=O)CCCCN[C@H]4[C@H](C5=CC=CC=C5)C4
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Chemical Name[1,1'-Biphenyl]-4-carboxamide, N-[(1S)-1-[[[(3-chlorophenyl)methyl]amino]carbonyl]-5-[[(1R,2S)-2-phenylcyclopropyl]amino]pentyl]-
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Miyamura S, et al. Org Biomol Chem. 2016 Sep 28;14(36):8576-85.
2. Sugino N, et al. Leukemia. 2017 Nov;31(11):2303-2314.
3. Ogasawara D, et al. Angew Chem Int Ed Engl. 2013 Aug 12;52(33):8620-4.
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