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N-Boc-PEG5-bromide
CAS No. 1392499-32-9
N-Boc-PEG5-bromide( —— )
Catalog No. M26767 CAS No. 1392499-32-9
N-Boc-PEG5-bromide is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). N-Boc-PEG5-bromide is a PROTAC linker based on PEG and Alkyl/ether.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
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Biological Information
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Product NameN-Boc-PEG5-bromide
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NoteResearch use only, not for human use.
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Brief DescriptionN-Boc-PEG5-bromide is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). N-Boc-PEG5-bromide is a PROTAC linker based on PEG and Alkyl/ether.
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DescriptionN-Boc-PEG5-bromide is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). N-Boc-PEG5-bromide is a PROTAC linker based on PEG and Alkyl/ether.(In Vitro):ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker. PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein.
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In VitroPROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins. ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker.
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In Vivo——
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Synonyms——
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PathwayOthers
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TargetOther Targets
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RecptorACSS2
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Research Area——
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Indication——
Chemical Information
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CAS Number1392499-32-9
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Formula Weight400.31
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Molecular FormulaC15H30BrNO6
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Purity>98% (HPLC)
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Solubility——
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SMILESCC(C)(C)OC(=O)NCCOCCOCCOCCOCCBr
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
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