N-Acetyl-D-Glucosamine

CAS No. 7512-17-6

N-Acetyl-D-Glucosamine( Acetylglucosamine | GlcNAc | Bio-NAG | GreenNAG )

Catalog No. M19074 CAS No. 7512-17-6

N-acetyl-D-Glucosamine (GlcNAc) is a monosaccharide derivative of glucose. It is released by the action of O-GlcNAcase, in mammalian systems from proteins that have been post-translationally modified with O-GlcNAc.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
500MG 37 In Stock
1G 43 In Stock

Biological Information

  • Product Name
    N-Acetyl-D-Glucosamine
  • Note
    Research use only, not for human use.
  • Brief Description
    N-acetyl-D-Glucosamine (GlcNAc) is a monosaccharide derivative of glucose. It is released by the action of O-GlcNAcase, in mammalian systems from proteins that have been post-translationally modified with O-GlcNAc.
  • Description
    Acetylglucosamine or N-acetylglucosamine is potentially for the treatment of irritable bowel syndrome. N-Acetylglucosamine (GlcNAc) is a monosaccharide that usually polymerizes linearly through (1,4)-β-linkages. GlcNAc is the monomeric unit of the polymer chitin, the second most abundant carbohydrate after cellulose. In addition to serving as a component of this homogeneous polysaccharide, GlcNAc is also a basic component of hyaluronic acid and keratin sulfate on the cell surface. GlcNAc has been reported to be an inhibitor of elastase release from human polymorphonuclear leukocytes (range 8–17% inhibition), however this is much weaker than the inhibition seen with N-acetylgalactosamine (range 92–100%).
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    Acetylglucosamine | GlcNAc | Bio-NAG | GreenNAG
  • Pathway
    Cell Cycle/DNA Damage
  • Target
    Topoisomerase
  • Recptor
    Human Endogenous Metabolite
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    7512-17-6
  • Formula Weight
    221.21
  • Molecular Formula
    C8H15NO6
  • Purity
    >98% (HPLC)
  • Solubility
    In Vitro:?DMSO : 125 mg/mL (565.07 mM)
  • SMILES
    OC1O[C@H](CO)[C@@H](O)[C@H](O)[C@H]1NC(C)=O
  • Chemical Name
    N-Acetyl-beta-D-glucosamine

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Liu F,etal.O-GlcNAcylation regulates phosphorylation of tau: a mechanism involved in Alzheimer's disease.Proc Natl Acad Sci U S A. 2004 Jul 20;101(29):10804-9.
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