Cart
sales@molnova.com
Methylnitronitrosoguanidine
CAS No. 70-25-7
Methylnitronitrosoguanidine( MNNG | 1-Methyl-3-nitro-1-nitrosoguanidine )
Catalog No. M20603 CAS No. 70-25-7
Methylnitronitrosoguanidine (MNNG) is an alkylating agent with toxic and mutagenic effects.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 25MG | 51 | In Stock |
|
| 50MG | 73 | In Stock |
|
| 100MG | Get Quote | In Stock |
|
| 200MG | Get Quote | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
-
Product NameMethylnitronitrosoguanidine
-
NoteResearch use only, not for human use.
-
Brief DescriptionMethylnitronitrosoguanidine (MNNG) is an alkylating agent with toxic and mutagenic effects.
-
DescriptionMethylnitronitrosoguanidine (MNNG) is an alkylating agent with toxic and mutagenic effects.(In Vitro):Methylnitronitrosoguanidine (MNNG, 0-1100 nM; 24 h) has toxic and mutagenic effects among 3 human diploid lymphoblast lines, MIT-2, WI-L2, and GM 130.(In Vivo):Methylnitronitrosoguanidine (MNNG; 200 mg/kg; p.o.) stimulates Wistar albino rats and increases the number of gastric cancer rats.
-
In Vitro——
-
In VivoAnimal Model:Male Wistar albino rats Dosage:200 mg/kg Administration:Oral administration, at 0 and 14th days Result:Had the incidence of gastric cancer in Wistar albino rats is 100%.
-
SynonymsMNNG | 1-Methyl-3-nitro-1-nitrosoguanidine
-
PathwayCell Cycle/DNA Damage
-
TargetDNA Alkylator
-
RecptorDNA alkylator
-
Research Area——
-
Indication——
Chemical Information
-
CAS Number70-25-7
-
Formula Weight147.09
-
Molecular FormulaC2H5N5O3
-
Purity>98% (HPLC)
-
SolubilityDMSO:125 mg/mL (849.82 mM)
-
SMILESCN(N=O)C(=N)N[N+]([O-])=O
-
Chemical Name——
Shipping & Storage Information
-
Storage(-20℃)
-
ShippingWith Ice Pack
-
Stability≥ 2 years
Reference
1.Slapikoff S A Andon B M Thilly W G . Comparison of toxicity and mutagenicity of methylnitrosourea methylnitronitrosoguanidine and ICR-191 among human lymphoblast lines[J]. Mutation Research 1980 70(3):365-371.
molnova catalog
related products
-
Methyl methanesulfon...
Methyl methanesulfonate is a DNA alkylator that modifies adenine (3-methyladenine) and guanine (7-methyladenine) respectively, resulting in base mismatch and replication disorders.
-
Chloroambucil
Chlorambucil(WR-139013; CB-1348) is a chemotherapy drug that has been mainly used in the treatment of chronic lymphocytic leukemia.
-
Dicycloplatin
Dicycloplatin (DCP) is a novel platinum analog that demonstrates significant antitumor activity against a variety of human cancer cell lines with IC50 of 25-30 nM.
