Menaquinone-4

CAS No. 863-61-6

Menaquinone-4( Vitamin K2 | Menaquinone K4 )

Catalog No. M20614 CAS No. 863-61-6

Menaquinone-4 ?is a vitamin K compound used as a hemostatic agent and also as adjunctive therapy for the pain of osteoporosis.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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100MG 37 In Stock
200MG Get Quote In Stock
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Biological Information

  • Product Name
    Menaquinone-4
  • Note
    Research use only, not for human use.
  • Brief Description
    Menaquinone-4 ?is a vitamin K compound used as a hemostatic agent and also as adjunctive therapy for the pain of osteoporosis.
  • Description
    Menaquinone-4 ?is a vitamin K compound used as a hemostatic agent and also as adjunctive therapy for the pain of osteoporosis.(In Vitro):Menaquinone-4 (MK-4, 0, 1, 5, 10 μM) increases the ALP activity in Caco-2 cells. Menaquinone-4 (1 μM) significantly increases intensities of hSI expression.(In Vivo):Menaquinone-4 (K2, 0.2 g/kg diet) in HF-K2 group produces epididymal fat in C57BL/6J mice, and also increases the bone density of mice.
  • In Vitro
    Menaquinone-4 (MK-4, 0, 1, 5, 10 μM) increases the ALP activity in Caco-2 cells. Menaquinone-4 (1 μM) significantly increases intensities of hSI expression.
  • In Vivo
    Menaquinone-4 (K2, 0.2 g/kg diet) in HF-K2 group produces epididymal fat in C57BL/6J mice, and also increases the bone density of mice.
  • Synonyms
    Vitamin K2 | Menaquinone K4
  • Pathway
    Others
  • Target
    Other Targets
  • Recptor
    Others
  • Research Area
    Others
  • Indication
    osteoporosis

Chemical Information

  • CAS Number
    863-61-6
  • Formula Weight
    444.65
  • Molecular Formula
    C31H40O2
  • Purity
    >98% (HPLC)
  • Solubility
    DMSO:20.83 mg/mL (46.85 mM)
  • SMILES
    CC(C)=CCC\C(C)=C\CC\C(C)=C\CC\C(C)=C\CC1=C(C)C(=O)c2ccccc2C1=O
  • Chemical Name
    2-methyl-3-((2E6E10E)-371115-tetramethylhexadeca-261014-tetraen-1-yl)naphthalene-14-dione

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Kim M Na W Sohn C . Vitamin K1 (phylloquinone) and K2 (menaquinone-4) supplementation improves bone formation in a high-fat diet-induced obese mice[J]. Journal of Clinical Biochemistry and Nutrition 2013 53(2):108-113.
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