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MeAIB

CAS No. 2566-34-9

MeAIB( —— )

Catalog No. M35186 CAS No. 2566-34-9

MeAIB is an N-acetyltransferase inhibitor that inhibits SNAT2-related signaling pathways. MeAIB is a specific substrate for amino acid transport system a (ATA1).

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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Biological Information

  • Product Name
    MeAIB
  • Note
    Research use only, not for human use.
  • Brief Description
    MeAIB is an N-acetyltransferase inhibitor that inhibits SNAT2-related signaling pathways. MeAIB is a specific substrate for amino acid transport system a (ATA1).
  • Description
    MeAIB (α-(Methylamino)isobutyric acid) is a specific?substrate for amino acid transport system A (ATA1). ATA mediate the uptake of short-chain neutral amino acids in a Na+-dependent manner.
  • In Vitro
    ATA3 is a new subtype of amino acid transport system A, primarily expressed in the liver and skeletal muscle. ATA1 (also known as GlnT) and ATA2 (also known as SAT2), have been cloned from rat and human tissues. These transporters mediate the uptake of short-chain neutral amino acids in a Na+-dependent manner.
  • In Vivo
    ——
  • Synonyms
    ——
  • Pathway
    Others
  • Target
    Other Targets
  • Recptor
    Others
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    2566-34-9
  • Formula Weight
    117.15
  • Molecular Formula
    C5H11NO2
  • Purity
    >98% (HPLC)
  • Solubility
    In Vitro:?H2O : 100 mg/mL (853.61 mM; Ultrasonic)DMSO : 50 mg/mL (426.80 mM; ultrasonic and warming and adjust pH to 2 with 1M HCl and heat to 60°C)
  • SMILES
    CNC(C)(C)C(O)=O
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. M Sugawara, et al. Structure and function of ATA3, a new subtype of amino acid transport system A, primarily expressed in the liver and skeletal muscle. Biochim Biophys Acta. 2000 Dec 20;1509(1-2):7-13.?
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