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Mal-amido-PEG7-acid

CAS No. 2112731-42-5

Mal-amido-PEG7-acid( Mal-NH-PEG7-COOH | Maleimide-NH-PEG7-CH2CH2COOH )

Catalog No. M26749 CAS No. 2112731-42-5

Mal-amido-PEG7-acid is a PEG-based PROTAC linker that can be used to synthesize PROTACs.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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Biological Information

  • Product Name
    Mal-amido-PEG7-acid
  • Note
    Research use only, not for human use.
  • Brief Description
    Mal-amido-PEG7-acid is a PEG-based PROTAC linker that can be used to synthesize PROTACs.
  • Description
    Mal-amido-PEG7-acid is a PEG-based PROTAC linker that can be used to synthesize PROTACs.(In Vitro):PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins. PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein.
  • In Vitro
    PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
  • In Vivo
    ——
  • Synonyms
    Mal-NH-PEG7-COOH | Maleimide-NH-PEG7-CH2CH2COOH
  • Pathway
    Others
  • Target
    Other Targets
  • Recptor
    HtrA2
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    2112731-42-5
  • Formula Weight
    548.586
  • Molecular Formula
    C24H40N2O12
  • Purity
    >98% (HPLC)
  • Solubility
    ——
  • SMILES
    OC(=O)CCOCCOCCOCCOCCOCCOCCOCCNC(=O)CCN1C(=O)C=CC1=O
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Cilenti L, et, al. Characterization of a novel and specific inhibitor for the pro-apoptotic protease Omi/HtrA2. J Biol Chem. 2003 Mar 28;278(13):11489-94.
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