Mal-amide-PEG8-Val-Ala-PAB-PNP( —— )

Catalog No. M37128 CAS No. 2210247-59-7

Mal-amide-PEG8-Val-Ala-PAB-PNP is a cleavable linker used in the production of antibody-drug conjugates (ADCs), enabling the attachment of cytotoxic drugs to antibodies for targeted delivery .

Purity : >98% (HPLC)

COA

Datasheet

HNMR

HPLC

MSDS

Handing Instructions

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5MG	227	Get Quote
10MG	341	Get Quote
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Biological Information

Product Name

Mal-amide-PEG8-Val-Ala-PAB-PNP
Note

Research use only, not for human use.
Brief Description

Mal-amide-PEG8-Val-Ala-PAB-PNP is a cleavable linker used in the production of antibody-drug conjugates (ADCs), enabling the attachment of cytotoxic drugs to antibodies for targeted delivery .
Description

Mal-amide-PEG8-Val-Ala-PAB-PNP is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
In Vitro

——
In Vivo

——
Synonyms

——
Pathway

Antibody Drug Conjugates (ADC)
Target

ADCs Linker/Click Chemistry
Recptor

ADC Linker
Research Area

——
Indication

——

Chemical Information

CAS Number

2210247-59-7
Formula Weight

1033.08
Molecular Formula

C48H68N6O19
Purity

>98% (HPLC)
Solubility

——
SMILES

N(C([C@@H](NC([C@@H](NC(CCOCCOCCOCCOCCOCCOCCOCCOCCNC(CCN1C(=O)C=CC1=O)=O)=O)C(C)C)=O)C)=O)C2=CC=C(COC(OC3=CC=C(N(=O)=O)C=C3)=O)C=C2
Chemical Name

——

Shipping & Storage Information

Storage

(-20℃)
Shipping

With Ice Pack
Stability

≥ 2 years

Reference

1. Junutula JR, et, al. Preparation of isoquinolidinobenzodiazepines and antibody conjugates thereof for treatment of hematological malignancies and solid tumors. WO2018053552

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