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MRZ 2-514

CAS No. 202808-11-5

MRZ 2-514 ( 8-bromo-4,5-dihydroxypyridazino[4,5-b]quinolin-1-one )

Catalog No. M26308 CAS No. 202808-11-5

MRZ 2-514 is a strychnine-insensitive modulatory site of the NMDA receptor (glycineB)antagonist with Ki of 33 μM.

Purity : >98% (HPLC)

COA

Datasheet

HNMR

HPLC

MSDS

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Biological Information

Product Name

MRZ 2-514
Note

Research use only, not for human use.
Brief Description

MRZ 2-514 is a strychnine-insensitive modulatory site of the NMDA receptor (glycineB)antagonist with Ki of 33 μM.
Description

MRZ 2-514 is a strychnine-insensitive modulatory site of the NMDA receptor (glycineB)antagonist with Ki of 33 μM.(In Vitro):MRZ 2-514 is against peak AMPA-induced currents with IC50 of 72.7 μM.(In Vivo):In mice, MRZ 2-514 has anticonvulsive action in the MES model, and the effect is prolonged by probenecid.
Synonyms

8-bromo-4,5-dihydroxypyridazino[4,5-b]quinolin-1-one
Pathway

Membrane Transporter/Ion Channel
Target

NMDAR
Recptor

——
Research Area

——
Indication

——

Chemical Information

CAS Number

202808-11-5
Formula Weight

308.1
Molecular Formula

C11H6BrN3O3
Purity

>98% (HPLC)
Solubility

——
SMILES

[O-][n+]1c2ccc(Br)cc2cc2c1c(=O)[nH][nH]c2=O
Chemical Name

——

Shipping & Storage Information

Storage

(-20℃)
Shipping

With Ice Pack
Stability

≥ 2 years

Reference

1.Raymond KN, Dertz EA, Kim SS. Enterobactin: an archetype for microbial iron transport. Proc Natl Acad Sci U S A. 2003 Apr 1;100(7):3584-8.

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