ML303

CAS No. 1638211-04-7

ML303( —— )

Catalog No. M23735 CAS No. 1638211-04-7

ML303 is an antagonist of pyrazolopyridine influenza virus nonstructural protein 1 (NS1) (IC90 : 155 nM).

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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Biological Information

  • Product Name
    ML303
  • Note
    Research use only, not for human use.
  • Brief Description
    ML303 is an antagonist of pyrazolopyridine influenza virus nonstructural protein 1 (NS1) (IC90 : 155 nM).
  • Description
    ML303 is an antagonist of pyrazolopyridine influenza virus nonstructural protein 1 (NS1) (IC90 : 155 nM).
  • In Vitro
    ML303 (20 μM, 6 h) treatment restore IFN-β mRNA levels in MDCK cells. Western Blot Analysis Cell Line:MDCK cells infected with A/PR/8/34, at a MOI of 2, for 6 hours.Concentration:20 μM.Incubation Time:6 hours. Result:Restored IFN-β mRNA levels in MDCK cells.
  • In Vivo
    ——
  • Synonyms
    ——
  • Pathway
    Microbiology/Virology
  • Target
    Influenza Virus
  • Recptor
    H1N1
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    1638211-04-7
  • Formula Weight
    399.37
  • Molecular Formula
    C21H16F3N3O2
  • Purity
    >98% (HPLC)
  • Solubility
    DMSO:10 mM
  • SMILES
    OC1=CC=C(C2=CC=NC3=C2C(C)=NN3C4=CC=C(C(F)(F)F)C=C4)C=C1OC
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Patnaik S, et al. Identification, design and synthesis of novel pyrazolopyridine influenza virus nonstructural protein 1 antagonists. Bioorg Med Chem Lett. 2019 May 1;29(9):1113-1119.
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