ML167

CAS No. 1285702-20-6

ML167( ML-167 | ML 167 )

Catalog No. M11167 CAS No. 1285702-20-6

A potent, selective CDC-like kinase 4 (CLK4) inhibitor with IC50 of 136 nM, >10-fold selectivity over Clk1, Clk2, Clk3, Dyrk1A/1B.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
2MG 41 Get Quote
5MG 63 Get Quote
10MG 105 Get Quote
25MG 217 Get Quote
50MG 371 Get Quote
100MG 552 Get Quote
200MG Get Quote Get Quote
500MG Get Quote Get Quote
1G Get Quote Get Quote

Biological Information

  • Product Name
    ML167
  • Note
    Research use only, not for human use.
  • Brief Description
    A potent, selective CDC-like kinase 4 (CLK4) inhibitor with IC50 of 136 nM, >10-fold selectivity over Clk1, Clk2, Clk3, Dyrk1A/1B.
  • Description
    A potent, selective CDC-like kinase 4 (CLK4) inhibitor with IC50 of 136 nM, >10-fold selectivity over Clk1, Clk2, Clk3, Dyrk1A/1B.
  • In Vitro
    ML167 has cell permeability in Caco-2 cells. ML167 contains a furan ring which liable to in vivo metabolism.
  • In Vivo
    ——
  • Synonyms
    ML-167 | ML 167
  • Pathway
    Cell Cycle/DNA Damage
  • Target
    CLK
  • Recptor
    CLK1|CLK2|CLK4|Dyrk1B
  • Research Area
    Other Indications
  • Indication
    ——

Chemical Information

  • CAS Number
    1285702-20-6
  • Formula Weight
    335.363
  • Molecular Formula
    C19H17N3O3
  • Purity
    >98% (HPLC)
  • Solubility
    DMSO: 62 mg/mL (184.9 mM); Ethanol: 11 mg/mL (32.8 mM); Water: <1 mg/mL ( < 1 mg/ml refers to the product slightly soluble or insoluble )
  • SMILES
    OCC1=CC=C(C2=CC3=C(NCC4=CC=C(C)O4)N=CN=C3C=C2)O1
  • Chemical Name
    5-[4-[[(5-Methyl-2-furanyl)methyl]amino]-6-quinazolinyl]-2-furanmethanol

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

molnova catalog
related products
  • SRI-29329

    A potent, specific CDC-like kinase (CLK) inhibitor with IC50 of 78, 16 and 86 nM for CLK1, 2 and4, respectively; shows no significant activity for CLK3, CDK1, CDK4 and CDK6 (IC50>1,000 nM).

  • ML197

    ML197 is a potent, selective small molecule inhibitor of Cdc2-like kinases (CLK) and DYRK with IC50 of 96/40/206 nM for CLK1/CLK4/Dyrk1A, respectively.

  • CLK inhibitor T3

    CLK inhibitor T3 (T3) is a highly potent, selective, and cell-based stable CDC-like kinase (CLK) inhibitor with 0.67, 15 and 110?nM for CLK1,2 and 3, respectively.