MDK1088
CAS No. 1350920-22-7
MDK1088( T.cruzi Inhibitor )
Catalog No. M19396 CAS No. 1350920-22-7
MDK-1088 (T.cruzi Inhibitor) is a Trypanosoma cruzi inhibitor.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
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Biological Information
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Product NameMDK1088
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NoteResearch use only, not for human use.
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Brief DescriptionMDK-1088 (T.cruzi Inhibitor) is a Trypanosoma cruzi inhibitor.
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DescriptionT.cruzi-IN-1 is a potent Trypanosoma cruzi inhibitor with an IC50 of 8 nM. T.cruzi-IN-1 a 4-trifluoromethyl substituted analog has the potential for both the acute and chronic stages of Chagas disease.
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In VitroT.cruzi-IN-1 inhibits Trypanosoma cruzi replication and has an IC50 of 61.6 μM for toxicity.
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In Vivo——
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SynonymsT.cruzi Inhibitor
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PathwayOthers
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TargetOther Targets
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RecptorTrypanosoma cruzi
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Research Area——
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Indication——
Chemical Information
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CAS Number1350920-22-7
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Formula Weight390.44
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Molecular FormulaC22H25F3N2O
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Purity>98% (HPLC)
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SolubilityDMSO:10 mM
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SMILESO=C(C1CN(Cc2ccc(C(F)(F)F)cc2)CCC1)N(Cc1ccccc1)C
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
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DL-2-AMINOOCTANOIC A...
DL-2-Aminooctanoic acid, also known as a-aminocaprylate or alpha-aminocaprylic acid, belongs to the class of organic compounds known as alpha-amino acids.
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Carmine
Ponceau 4R is a synthetic strawberry red azo dye that is a food colorant dye used in a variety of food products.
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Syk Inhibitor II hyd...
The impact of spleen tyrosine kinase (Syk) signaling might be prominent in lupus because (i) Syk is a shared downstream signaling molecule among circulating immune complex, LPS, and (1→3)-β-D-glucan (BG), and (ii) all of these factors are detectable in the serum of Fc gamma receptor IIb-deficient (FcgRIIb-/-) mice with sepsis. Syk inhibition downregulated several inflammatory pathways in FcgRIIb-/- macrophages activated with BG + LPS suggesting the potential anti-inflammatory impact of Syk inhibitors in lupus.
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