GDC046, a potent lead analog, has good kinase selectivity, physicochemical properties and pharmacokinetic profile.

Tea polyphenol also called green tea extract are a mixture of chemical compounds such as flavanoids and tannins found naturally in tea. Polyphenols are powerful antioxidants which can reduce the risk of developing coronary artery disease and a number of other health problems.

RC-3095, a selective GRPR antagonist, has been shown to have anti-inflammatory properties in different models of inflammation.